SHI supported the African Union Development Agency–NEPAD (AUDA-NEPAD) to prepare for the transition of the African Medicines Regulatory Harmonization (AMRH) initiative into the African Medicines Agency (AMA) following adoption of the AMA Treaty. The work focused on developing a continent-wide Country Engagement and Implementation Plan to align national regulators, policymakers, and regional bodies around a shared approach to AMA operationalisation.  SHI supported coordination and ensured disciplined execution, while leadership and decision-making remained with AUDA-NEPAD and African institutions.

The initiative strengthened readiness for treaty ratification and early AMA operationalisation, while maintaining continuity of existing AMRH programmes during a critical institutional transition.