SHI supported the ZAZIBONA collaborative medicines regulatory initiative, a SADC-based work-sharing mechanism led by participating national regulatory authorities.  The work strengthened coordination, continuity, and delivery of joint regulatory activities across countries, while national authorities retained full regulatory decision-making authority.

Coordination support, fiduciary oversight, and disciplined execution enabled the mechanism to function effectively across multiple jurisdictions.  This contributed to sustained joint assessments, improved operational processes, and strengthened performance tracking, supporting more efficient progression from joint review to national authorisation.